DNA Clusters - Chromosome 1 and Chromosome 2

We uploaded the raw DNA kits for Julie, Stewart and Clinton to the website GEDMatch.  GEDMatch is a free website that allows individuals from different DNA testing companies to share their test results and collaborate.

GEDMatch also offers users many different utilities to analyze raw DNA results. One of the utilities available is a 'One-to-many' matches. The utility is run for one person and it will provide a list of kits that share DNA with that person.

Using the 'One-to-many' matches utility a list of matches was generated for Julie, Stewart and Clinton. The results were compared to identify kits shared by all three cousins. The results returned 1,500 matches per cousin. Of the 4,500 matches analyzed there were 16 DNA kits that shared DNA with Julie, Stewart and Clinton.

These 16 sets of results were then run through the utility 'One-to-one' compare. The  'One-to-one' compare allows two DNA kits to be compared. This utility will determine if two kits share DNA. If the two kits do share DNA the utility will identify the shared segments by chromosome. The utility will also show the amount of DNA shared in centiMorgans(cM) by chromosome and in total. Once the amount of shared DNA is understood a genetic table can be consulted to have a better understanding of the potential relationship between the two individuals.

The results from the 'One-to-one' compare were compiled into a spreadsheet for further analysis. After reviewing the results the majority of the DNA matches  were concentrated on Chromosome 1. The graphic below shows the 10 DNA kits that share DNA with Julie on Chromosome 1. Further review of these kits indicates there are three sub-clusters of DNA.

DNA Matches on Chromosome 1

Chromosome 1 - A Sub-Cluster:

• This cluster of DNA matches occurs on Chromosome 1. 
• The start location is 164,433,319.
• The end location is 173,508,458.
• This cluster is made up of 7 DNA kits.
• There are 4 DNA kits that match the 3 Miller/Shoup cousins (Julie, Stewart and Clinton)
• One of the matches is in the range of a 3rd cousin to Stewart.
• The remainder of the matches are in the 4th cousin range to all 3 Miller/Shoup cousins.

Chromosome 1 - B Sub-Cluster:

• This cluster of DNA matches occurs on Chromosome 1. 
• The start location is 175,004,876
• The end location is 197,583,558
• This cluster is made up of 6 DNA kits.
• There are 3 DNA kits that match the 3 Miller/Shoup cousins (Julie, Stewart and Clinton)
• The  matches are in the 4th cousin range to all 3 Miller/Shoup cousins.

Chromosome 1 - C Sub-Cluster:

• This cluster of DNA matches occurs on Chromosome 1. 
• This match has overlaps with the matches in Chromosome 1-A and Chromosome 1-B. What makes this match different is there is no break in the segment. This match is represented by the dashed lines in the overall Chromosome 1 graphic. 
• The start location is 173,450,562
• The end location is 198,313,067
• This cluster is made up of 4 DNA kits.
• There is 1 DNA kits that match the 3 Miller/Shoup cousins (Julie, Stewart and Clinton)
• The match is in the 4th cousin range to all 3 Miller/Shoup cousins.

The results also indicated there was one cousin that matched Julie, Stewart and Clinton on Chromosome 2.

Chromosome 2 - A Sub-Cluster:

• This cluster of DNA matches occurs on Chromosome 2. 
• The start location is 202,838,641
• The end location is 212,302,918
• This cluster is made up of 4 DNA kits.
• There are 3 DNA kits that match the 3 Miller/Shoup cousins (Julie, Stewart and Clinton)
• There is 1 DNA kits that match the 3 Miller/Shoup cousins (Julie, Stewart and Clinton)
• The match is in the 4th cousin range to all 3 Miller/Shoup cousins.

Now What? How do we use this data? 

The next step in the process will be to contact each of the matches. If the match knows their family history and is willing to share who their ancestors with us it would be very helpful to our research. These matches are all distant cousins to Julie. If we can determine how these individuals descend from Henry H. Miller and Lydia Shoup we can eliminate those descendant lines from our search.